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Gene Symbol HDAC2
Synonyms HD2 | KDAC2 | RPD3 | YAF1
Gene Description HDAC2, histone deacetylase 2, is a member of the class I HDAC family that functions in deacetylation of histone and non-histone proteins to regulate various cell cycle and developmental processes via transcriptional repression of target genes (PMID: 25072962, PMID: 30096875). HDAC2 is overexpressed in variety of cancers in which Tp53 is a critical regulatory target during tumorigenesis (PMID: 25072962).
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