Gene Detail

Gene Symbol HES1
Synonyms bHLHb39 | HES-1 | HHL | HRY
Gene Description HES1, transcription factor HES-1, is a transcriptional repressor of genes that require a bHLH protein for their transcription and is a downstream target of Notch signaling and plays a role in T-cell development (PMID: 27066918). Hes1 overexpression has been observed in a variety of solid tumor types (PMID: 25139105; PMID: 25234168; PMID: 24492635, PMID: 27066918).
Entrez Id 3280
Chromosome 3
Map Location 3q29
Canonical Transcript NM_005524

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