Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Synonyms||API1 | c-IAP1 | cIAP1 | Hiap-2 | HIAP2 | MIHB | RNF48|
|Gene Description||BIRC2, baculoviral IAP repeat containing 2, belongs to the IAP family, and is involved in regulating TNF and NF-kB activated signaling pathways (PMID: 21653699). BIRC2 mutations have been observed in lymphoid and epithelial tumors, loss of BIRC2 has been demonstrated in multiple myeloma (PMID: 26094954), and BIRC2 amplification has been detected in cervix carcinoma (PMID: 22733500).|