Gene Detail
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| Gene Symbol | ID4 | ||||||||||
| Synonyms | bHLHb27 | IDB4 | ||||||||||
| Gene Description | ID4, inhibitor of DNA binding 4, HLH protein, is a member of the Id family of helix-loop-helix (HLH) proteins, which bind other HLH family members to negatively regulate their activity (PMID: 25248477, PMID: 16034366, PMID: 28143562). Dysregulation of Id4 expression is associated with several tumor types including glioblastoma (PMID: 20842217), prostate cancer (PMID: 28252832), and the basal-like subtype of breast cancer (PMID: 28652379). | ||||||||||
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