Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol IFIT1
Synonyms C56 | G10P1 | IFI-56 | IFI-56K | IFI56 | IFIT-1 | IFNAI1 | ISG56 | P56 | RNM561
Gene Description IFIT1, interferon induced protein with tetratricopeptide repeats 1, is a member of the IRF-inducible gene family that plays a role in the immune defense against RNA viruses and may regulate expression of inflammatory cytokines (PMID: 30282041, PMID: 31921891). Overexpression of Ifit1 in glioblastoma has been associated with improved prognosis and increased survival (PMID: 26980050), while overexpression in head and neck squamous cell carcinoma is associated with poor prognosis (PMID: 31977029).


Additional content available in CKB BOOST