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Gene Symbol RSPO4
Synonyms C20orf182 | CRISTIN4
Gene Description RSPO4, R-spondin 4, encodes for one of the secreted proteins in the TSR1-containing protein family, which plays a role in canonical Wnt signaling and nail development (PMID: 22439850). RSPO4 overexpression has been identified in serous endometrioid adenocarcinoma (PMID: 24894155) and breast cancer (PMID: 28472820).
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