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Gene Symbol IFNGR1
Synonyms CD119 | IFNGR | IMD27A | IMD27B
Gene Description IFNGR1, interferon gamma receptor 1, is the ligand binding subunit that forms a dimer with IFNGR2 to form a cytokine receptor for IFNG, which activates the JAK/STAT signaling pathway (PMID: 24453034). Germline variants in Ifngr1 may be associated with increased risk of gastric cancer (PMID: 24453034, PMID: 18593809).
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