Gene Detail


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Gene Symbol IGF2
Synonyms C11orf43 | GRDF | IGF-II | PP9974 | SRS3
Gene Description IGF2, insulin like growth factor 2, encodes for a growth factor involved in cell growth and differentiation processes that occur during embyronic development and adult life (PMID: 18308616). Overexpression of IGF2 has been linked to mesenchymal tumors and hepatocellular carcinoma and may be associated with worse prognosis in breast cancer, esophageal cancer, chronic myeloid leukemia (PMID: 24080445), colorectal cancer (PMID: 31623387), and adrenocortical carcinoma (PMID: 31378849).
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