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Gene Symbol IGFBP1
Synonyms AFBP | hIGFBP-1 | IBP1 | IGF-BP25 | PP12
Gene Description IGFBP1, insulin-like growth factor binding protein 1, is a member of the IGF-binding protein (IGFBP) family that is mainly expressed by the liver and circulates in the plasma to regulate cell migration and survival (PMID: 27152521). Aberrant expression of Igfbp1 has been observed in colorectal cancer liver metastasis (PMID: 27152521) and in endometrial cancer (PMID: 26802879).
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