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Gene Symbol IRAK1
Synonyms IRAK | pelle
Gene Description IRAK1, interleukin-1 receptor-associated kinase, mediates TLR and IL1R signaling and regulates immune response (PMID: 17890055). Overexpression of Irak1 has been observed in patients with myelodysplastic syndrome (PMID: 23845443), breast cancer (PMID: 26503059), and hepatocellular carcinoma (PMID: 29483095).
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