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Gene Symbol IRF1
Synonyms IMD117 | IRF-1 | MAR
Gene Description IRF1, interferon regulatory factor 1, is a transcription factor that plays a role in immune response and the expression of anti-viral genes (PMID: 31156620), apoptosis (PMID: 14762441), DNA damage response (PMID: 7637809) and cell proliferation (PMID: 11846974). Mutations in IRF1 are associated with gastric cancer (PMID: 9679752), leukemia (PMID: 7936656), and colorectal cancer (PMID: 31827213).
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