Gene Detail


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Gene Symbol AR
Synonyms AIS | AR8 | DHTR | HUMARA | HYSP1 | KD | NR3C4 | SBMA | SMAX1 | TFM
Gene Description AR, androgen receptor, belongs to the nuclear hormone receptor family, which acts as a transcription factor, resulting in either transcription or repression of specific genes (PMID: 24909511, PMID: 21784131). AR overexpression leads to ligand independent activation of AR and is common in prostate cancer (PMID: 16598769) and AR mutations and constitutively active splice variants are also commonly observed in prostate cancer (PMID: 31868960).
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