Gene Detail

Gene Symbol ITPR2
Synonyms ANHD | CFAP48 | INSP3R2 | IP3R2
Gene Description ITPR2, inositol 1,4,5-trisphosphate receptor type 2, regulates intracellular Ca2+ release (PMID: 25499268) and plays a role in the cell cycle and proliferation (PMID: 25779662). An in-frame fusion of the ETV6 promoter with the C-terminal portion of Itpr2 has been observed in breast cancer (PMID: 20033038) and overexpression of Itpr2 has been observed in AML (PMID: 25779662).
Entrez Id 3709
Chromosome 12
Map Location 12p11.23
Canonical Transcript NM_002223

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