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Gene Symbol LCK
Synonyms IMD22 | LSK | p56lck | pp58lck | YT16
Gene Description LCK, LCK proto-oncogene, Src family tyrosine kinase, plays a role in T-cell receptor signaling and T-cell development (PMID: 19290918) and is activated upon antigen presentation by MHC (PMID: 30660961). LCK overexpression has been demonstrated in chronic lympocytic leukemia (PMID: 23505068) and promotes proliferation of acute myeloid leukemia cells in culture (PMID: 30660961).
Additional content available in CKB BOOST