Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol LDLR
Synonyms FH | FHC | FHCL1 | LDLCQ2
Gene Description LDLR, low density lipoprotein receptor, is a transmembrane protein that mediates endocytosis of lipoproteins, and is involved in cholesterol homeostasis and lipid metabolism (PMID: 22461740, PMID: 19299327, PMID: 15952897). A LDLR-ROS1 fusion has been identified in lung adenocarcinoma (PMID: 35299735).
Additional content available in CKB BOOST