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Gene Symbol LTK
Synonyms TYK1
Gene Description LTK, leukocyte receptor tyrosine kinase, is an orphan receptor with unknown ligand, but is very similar to ALK and is believed to be involved in growth and development (PMID: 22347506). Expression of LTK engineered to harbor mutations at sites analogous to transforming ALK mutations demonstrated transforming ability in cell assays (PMID: 22347506).
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