Gene Detail


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Gene Symbol MAGEA6
Synonyms CT1.6 | MAGE-3b | MAGE3B | MAGE6
Gene Description MAGEA6, melanoma-associated antigen 6, is a member of the cancer testis antigen (CTA) family that has normal, restricted expression in the testis (PMID: 29448247) and also functions as a cancer-specific ubiquitin ligase that degradates AMPK (PMID: 29448247, PMID: 29024810). Abnormal expression of Magea6 has been reported in a number of solid tumor types including, glioma (PMID: 29024810), renal cell carcinoma (PMID: 29448247), and head and neck squamous cell carcinoma (PMID: 25564441).
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