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Gene Symbol PIM3
Synonyms pim-3
Gene Description PIM3, serine/threonine-protein kinase pim-3, phosphorylates BAD to prevent apoptosis and promote cell survival and therefore, likely functions as an oncogene (PMID: 30370255). Overexpression of Pim3 has been reported in a variety of tumor types, including hepatoblastoma (PMID: 29854306), pancreatic (PMID: 26547690), prostate (PMID: 27826135), colorectal (PMID: 17270021), and gastric (PMID: 24488669).


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