Gene Detail

Gene Symbol AFDN
Synonyms AF6 | l-afadin | MLL-AF6 | MLLT4
Gene Description AFDN, afadin, adherens junction formation factor; encodes Afadin, which has roles in cell adhesion, migration, survival, and differentiation (PMID: 23481206). AFDN is a frequent binding partner for MLL in acute leukemias, and loss of Afadin expression is associated with poor prognosis in breast cancer (PMID: 20395419, PMID: 21478912).
Entrez Id 4301
Chromosome 6
Map Location 6q27
Canonical Transcript XM_005266996

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