Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||leB | MUC5 | mucin | TBM|
|Gene Description||MUC5AC, mucin 5AC, oligomeric mucus/gel-forming, encodes a mucin glycoprotein that is secreted from goblet cells and plays a role in the protection and lubrication of exposed surfaces, serving as a component of human tears and mucosal secretions (PMID: 9888425), and is a key factor in the innate mucosal defense, including involvement in allergic inflammation (PMID: 25687754). Decreased MUC5AC expression has been observed in gastric adenocarcinoma (PMID: 23801416) while overexpression of MUC5AC has been identified in colorectal cancer (PMID: 32098629).|