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Gene Symbol MYD88
Synonyms IMD68 | MYD88D | WM1
Gene Description MYD88, MYD88 innate immune signal transduction adaptor, is an adapter protein involved in Toll-like receptor and IL-1 signaling in the immune response, cytokine secretion, and inflammatory response (PMID: 19506249, PMID: 30086464). MYD88 mutations are frequently identified in hematological malignancies (PMID: 25132836, PMID: 29703722), including B-cell non-hodgkin lymphomas (PMID: 30203262).
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