Gene Detail
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| Gene Symbol | MYO5A | ||||||||||
| Synonyms | GS1 | MYH12 | MYO5 | MYR12 | ||||||||||
| Gene Description | MYO5A, myosin VA, functions as an actin-based motor that transports molecules to the plasma membrane (PMID: 23176491) and plays a role in malignant transformation in melanoma (PMID: 23652798). MYO5A fusions with ROS1, NTRK3, and ALK have been observed in Spitz naevi and spitzoid melanomas (PMID: 24445538, PMID: 27477320, PMID: 28433076, PMID: 32701692) and overexpression of Myo5a has been reported in melanoma (PMID: 23652798). | ||||||||||
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