Gene Detail
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| Gene Symbol | ATIC | ||||||||||
| Synonyms | AICAR | AICARFT | HEL-S-70p | IMPCHASE | PURH | ||||||||||
| Gene Description | ATIC, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase, is part of the purine biosynthetic pathway that catalyzes the two steps in de novo inosine 5'-monophosphate synthesis (PMID: 11948179, PMID: 30337562). An ATIC-ALK fusion has been observed in anaplastic large cell lymphoma (PMID: 10702393). | ||||||||||
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