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Gene Symbol ATIC
Synonyms AICAR | AICARFT | HEL-S-70p | IMPCHASE | PURH
Gene Description ATIC, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase, is part of the purine biosynthetic pathway that catalyzes the two steps in de novo inosine 5'-monophosphate synthesis (PMID: 11948179, PMID: 30337562). ATIC fusions with ALK have been observed in anaplastic large cell lymphoma (PMID: 10702393).


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