Gene Detail

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Gene Symbol NFIB
Synonyms CTF | HMGIC/NFIB | MACID | NF-I/B | NF1-B | NFI-B | NFI-RED | NFIB2 | NFIB3
Gene Description NFIB, nuclear factor I B, encodes for a transcription factor involved in developmental regulation, primarily, in the lung and brain (PMID: 20725108). NFIB fusions and amplifications have been associated with multiple cancer types including prostate cancer, glioblastoma, and lipomas (PMID: 27083054), including an MYB-NFIB has been identified in adenoid cystic carcinoma of head and neck (PMID: 19841262, PMID: 31301736, PMID: 31028361, PMID: 30269389) and prostatic basal cell carcinoma (PMID: 31189999).


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