Gene Detail

Gene Symbol NOTCH3
Synonyms CADASIL | CADASIL1 | CASIL | IMF2 | LMNS
Gene Description NOTCH3 is a transmembrane receptor, which plays a role in cell fate regulation, proliferation, and survival. NOTCH3 amplification has been implicated in the development of ovarian high-grade serous carcinoma (PMID: 20001801).
Entrez Id 4854
Chromosome 19
Map Location 19p13.12
Canonical Transcript NM_000435


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