Gene Detail

Gene Symbol NOTCH4
Synonyms INT3
Gene Description NOTCH4 is a transmembrane receptor, which plays a role in cell fate regulation, proliferation, and survival (PMID: 24403446). NOTCH4 overexpression in TNBC plays a role in proliferation and invasiveness (PMID: 24403446) and has also been observed in tamoxifen-resistant breast cancer (PMID: 28108315) and OSCC (PMID: 27197026).
Entrez Id 4855
Chromosome 6
Map Location 6p21.32
Canonical Transcript NM_004557


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