Gene Detail

Gene Symbol NTRK3
Synonyms gp145(trkC) | GP145-TrkC | TRKC
Gene Description NTRK3 (neurotrophic tyrosine kinase, receptor, type 3) is a membrane receptor tyrosine kinase that binds neurotrophins, initiating signaling cascades that lead to cell growth and differentiation. NTRK3 has been described as a dependence receptor that induces apoptosis when ligand-fee and so may be a tumor suppressor or oncogene, depending on context (PMID: 23396845).
Entrez Id 4916
Chromosome 15
Map Location 15q25.3
Canonical Transcript NM_001012338


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