Gene Detail

Gene Symbol PAK1
Synonyms IDDMSSD | PAKalpha
Gene Description PAK1, p21 protein (Cdc42/Rac)-activated kinase 1, is a Group I PAK family member that functions as an effector for Rac and Cdc42 signaling, and is involved in regulation of cell signaling, proliferation, migration, and survival (PMID: 23125950, PMID: 23162742). PAK1 amplified and over expression in several tumor types (PMID: 23125950, PMID: 24529727).
Entrez Id 5058
Chromosome 11
Map Location 11q13.5-q14.1
Canonical Transcript NM_002576


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