Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | PCBP1 | ||||||||||
| Synonyms | HEL-S-85 | hnRNP-E1 | hnRNP-X | HNRPE1 | HNRPX | ||||||||||
| Gene Description | PCBP1, poly(rC) binding protein 1, encodes a member of the heterogeneous nuclear ribonucleoproteins, functioning as an RNA-binding and DNA-binding protein (PMID: 16979592), and plays a role in regulating transcription and translational activities, and mRNA stabilization (PMID: 17389360, PMID: 20609352, PMID: 18656558). PCBP1 mutations have been identified in Burkitt lymphoma (PMID: 26173642) and decreased expression of PCBP1 has been identified in gastric cancer (PMID: 29138420). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
