Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Synonyms||PTC4 | RET/PCM-1|
|Gene Description||PCM1, pericentriolar material 1, is a centriolar satellite protein, which recruits microtubule and dynactin-dependent proteins for appropriate microtubule organization (PMID: 12403812). A PCM1-RET fusion has been identified in papillary thyroid carcinoma (PMID: 10980597), PCM1 fusions with other genes have been observed in hematological cancers (PMID: 29797824, PMID: 26522767, PMID: 31085913, PMID: 29169164), and both overexpression and amplification of PCM1 have been linked to myeloid leukemias (PMID: 10980597, PMID: 23431203).|