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Gene Symbol PCNA
Synonyms ATLD2
Gene Description PCNA, proliferating cell nuclear antigen, plays an important role in diverse cellular functions, including DNA replication, repair, regulation of cell cycle, chromatin assembly, and transcription, and undergoes post-translational modifications and interacts with multiple proteins (PMID: 24655521, PMID: 19442257, PMID: 9038370). Overexpression of Pcna has been demonstrated in prostate adenocarcinoma (PMID: 21031434), and is associated with reduced survival in colorectal cancer (PMID: 8095852).
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