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Gene Symbol EGFL7
Synonyms NEU1 | VE-STATIN | ZNEU1
Gene Description EGFL7, EGF like domain multiple 7, encodes a secreted growth factor that is primarily expressed in endothelial cells, promotes angiogenesis, and plays a role in the regulation of Notch signaling (PMID: 22160377). EGFL7 mutations have been observed in acute myeloid leukemia (PMID: 27798625), and overexpression has been identified in hepatocellular carcinoma (PMID: 29970668) and acute myeloid leukemia (PMID: 28533390).
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