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Gene Symbol TNFRSF12A
Synonyms CD266 | FN14 | TWEAKR
Gene Description TNFRSF12A, tumor necrosis factor receptor superfamily member 12A, is a membrane receptor for Tnfsf12, which regulates diverse cellular functions including proliferation, differentiation, and inflammation (PMID: 28639899). TNFRSF12A expression level has been associated with prognosis of breast, gastric, lung, and liver cancers (PMID: 28639899) and hypomethylation of TNFRSF12A has been observed in hepatocellular carcinoma (PMID: 31998364).
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