Gene Detail
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| Gene Symbol | DDX41 | ||||||||||
| Synonyms | ABS | MPLPF | ||||||||||
| Gene Description | DDX41, DEAD-box helicase 41, encodes an SF2 superfamily member that plays a role in innate immunity, and has putative involvement in mRNA splicing and post-transcriptional regulation (PMID: 27502187, PMID: 28547672). DDX41 mutations, both somatic and germline, are associated with myeloid neoplasms including myelodysplastic syndrome and acute myeloid leukemia (PMID: 25920683, PMID: 31484648). | ||||||||||
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