Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Synonyms||EPLIN | LDLCQ8 | SREBP3|
|Gene Description||LIMA1, LIM domain and actin-binding protein 1, plays a role in regulating the polymerization state of actin, cross linking of actin bundles (PMID: 26350886), and cholesterol homeostasis (PMID: 29941963). Decreased expression of Lima1 has been observed in prostate and breast cancers (PMID: 26350886) and a LIMA1-ROS1 has been identified in lung cancer (PMID: 25264305).|