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Gene Symbol LIMA1
Synonyms EPLIN | LDLCQ8 | SREBP3
Gene Description LIMA1, LIM domain and actin-binding protein 1, plays a role in regulating the polymerization state of actin, cross linking of actin bundles (PMID: 26350886), and cholesterol homeostasis (PMID: 29941963). Decreased expression of Lima1 has been observed in prostate and breast cancers (PMID: 26350886) and a LIMA1-ROS1 has been identified in lung cancer (PMID: 25264305).
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