Gene Detail

Gene Symbol DTL
Synonyms CDT2 | DCAF2 | L2DTL | RAMP
Gene Description DTL, denticleless E3 ubiquitin protein ligase homolog, encodes for a protein that plays a significant role in cell cycle control, including preventing additional replication via CDT1 regulation (PMID: 17085480). DTL amplification and/or overexpression has been found to be associated with several cancer types including gastric, hepatocellular carcinoma, breast, and Ewing sarcoma (PMID: 26472028).
Entrez Id 51514
Chromosome 1
Map Location 1q32.3
Canonical Transcript NM_016448

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