Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||c-sis | IBGC5 | PDGF-2 | PDGF2 | SIS | SSV|
|Gene Description||PDGFB, platelet derived growth factor subunit B, is a growth factor that signals through PDGFRs and plays a role in regulation of development, cell proliferation, cell migration (PMID: 18483217), and angiogenesis (PMID: 32235327). Overexpression of PDGFB has been implicated in several tumor types (PMID: 24359404), including oral squamous cell carcinoma (PMID: 32235327), and a fusion with COL1A1 has been reported in dermatofibrosarcoma protuberans (PMID: 31870844, PMID: 31353504).|