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Gene Symbol TRIM33
Synonyms ECTO | PTC7 | RFG7 | TF1G | TIF1G | TIF1GAMMA | TIFGAMMA
Gene Description TRIM33, tripartite motif containing 33, has multiple functions including E3-ubiquitin ligase and transcriptional coregulatory activity, and plays a role in DNA repair, cell-cycle, and hematopoeisis (PMID: 25639486, PMID: 26282171). A TRIM33-RET fusion has been identified in lung adenocarcinoma (PMID: 23533264) and papillary thyroid carcinoma (PMID: 10741739), and a TRIM33-NTRK1 fusion has been observed in papillary thyroid carcinoma (PMID: 30664823).


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