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Gene Symbol PDPK1
Synonyms PDK1 | PDPK2 | PDPK2P | PRO0461
Gene Description PDPK1, 3-phosphoinositide dependent protein kinase 1, encodes for a serine/threonine kinase that is responsible for phosphorylating the activation domain of the AGC protein kinases (PMID: 24039447). Overexpression and amplification of PDPK1 has been demonstrated to result in transformation in several types of cancer cells (PMID: 24039447, PMID: 25269480).


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