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Gene Symbol PGR
Synonyms NR3C3 | PR
Gene Description PGR, progesterone receptor, is a member of the steroid nuclear receptor superfamily, which is activated by progesterone binding and mediates downstream signaling (PMID: 24287036). PGR expression is an indicator of estrogen-ERalpha activity and is used as a prognostic and predictive biomarker in breast cancer (PMID: 20436503, PMID: 23280579, PMID: 20586616, PMID: 30120700).
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