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Gene Symbol PIGA
Synonyms GPI3 | MCAHS2 | NEDEPH | PIG-A | PNH1
Gene Description PIGA, phosphatidylinositol glycan anchor biosynthesis class A, is an enzyme essential for biosynthesis of glycosyl-phosphatidyl inositol (GPI) anchors, which play a role in linking proteins to the cell surface (PMID: 8647522, PMID: 25885527, PMID: 28516949). PIGA mutations are associated with aplastic anemia (PMID: 27121470).
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