Gene Detail

Gene Symbol PIK3CB
Synonyms P110BETA | PI3K | PI3KBETA | PIK3C1
Gene Description PIK3CB, phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, activates AKT/mTOR signaling to promote cell proliferation (PMID: 23411347). PIK3CB mutations have been identified in breast cancer, glioblasoma, and colorectal cancer (PMID: 29326882).
Entrez Id 5291
Chromosome 3
Map Location 3q22.3
Canonical Transcript NM_006219


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