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|Synonyms||P110BETA | PI3K | PI3KBETA | PIK3C1|
|Gene Description||PIK3CB, phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, activates AKT/mTOR signaling to promote cell proliferation (PMID: 23411347). PIK3CB mutations have been identified in breast cancer, glioblastoma, and colorectal cancer (PMID: 29326882).|