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|Synonyms||APDS | IMD14 | p110D | P110DELTA | PI3K|
|Gene Description||PIK3CD, phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta, is one of four Class I phosphoinositide 3-kinases that is predominantly expressed in leukocytes and regulates leukocyte proliferation and differentiation (PMID: 23330955). PIK3CD has been identified as a hub and/or driver gene in nasopharyngeal carcinoma (PMID: 30830589) and gastric cancer (PMID: 32034058), and overexpression of Pik3cd has been reported in hepatocellular carcinoma (PMID: 30300952) and other solid tumors (PMID: 32556179).|