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|Synonyms||ARCND2 | PI-PLC|
|Gene Description||PLCB4, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4, catalyzes the production of diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) (PMID: 22560091). Gain of function mutations in PLCB4 have been identified in uveal melanoma (PMID: 26683228).|