Gene Detail

Gene Symbol PLCB4
Synonyms ARCND2 | PI-PLC
Gene Description PLCB4, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4, catalyzes the production of diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) (PMID: 22560091). Gain of function mutations in PLCB4 have been identified in uveal melanoma (PMID: 26683228).
Entrez Id 5332
Chromosome 20
Map Location 20p12.3-p12.2
Canonical Transcript NM_182797

Additional content available in CKB BOOST