| Gene Symbol | POLE |
| Synonyms | CRCS12 | FILS | POLE1 |
| Gene Description | POLE, polymerase (DNA directed), epsilon, catalytic subunit, is the catalytic subunit of DNA polymerase epsilon, which mediates DNA repair and replication (PMID: 26822575). POLE mutations are frequently identified in cancers, particularly in colorectal and endometrial cancers (PMID: 26822575). |
| Entrez Id | 5426 |
| Chromosome | 12 |
| Map Location | 12q24.33 |
| Canonical Transcript | NM_006231 |