Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol RBM47
Synonyms NET18
Gene Description RBM47, RNA binding motif protein 47, plays a key role in post-transcriptional regulation of RNA, specifically C to U RNA editing, by interacting with APOBEC1 (PMID: 24916387, PMID: 30309881, PMID: 29844590), regulates alternative splicing via acting as a splicing factor (PMID: 27044866, PMID: 31358901), and controls the TP53-p21 signaling axis (PMID: 31511650). Decreased expression of RBM47 has been identified in colorectal cancer (PMID: 28680090) and breast cancer (PMID: 24898756), and a fusion with RBM47 and CDK12 has been identified in prostate cancer (PMID: 31592503).


Additional content available in CKB BOOST