Gene Detail

Gene Symbol PPP2R1A
Synonyms MRD36 | PP2A-Aalpha | PP2AA | PP2AAALPHA | PR65A
Gene Description PPP2R1A, protein phosphatase 2, regulatory subunit A, alpha, is a scaffold subunit of the major serine-threonine phosphatase PP2A, which has roles in cell signaling, proliferation, differentiation, and apoptosis (PMID: 23454242). PPP2R1A is frequently mutated in uterine serous carcinoma, and serous endometrial cancer (PMID: 23454242, PMID: 22888282).
Entrez Id 5518
Chromosome 19
Map Location 19q13.41
Canonical Transcript NM_014225


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