Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | PPP2R1A | ||||||||||
| Synonyms | HJS2 | MRD36 | PP2A-Aalpha | PP2AA | PP2AAALPHA | PR65A | ||||||||||
| Gene Description | PPP2R1A, protein phosphatase 2 scaffold subunit Aalpha, contains 15 Huntingtin-Elongation-A subunit-TOR (HEAT) repeats (PMID: 31214504) and is a scaffold subunit of the major serine-threonine phosphatase PP2A, which has roles in cell signaling, proliferation, differentiation, and apoptosis (PMID: 23454242). PPP2R1A is frequently mutated in uterine serous carcinoma and serous endometrial cancer (PMID: 23454242, PMID: 22888282, PMID: 31214504). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
