Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol PRKAA1
Synonyms AMPK | AMPKa1
Gene Description PRKAA1, protein kinase AMP-activated catalytic subunit alpha 1, is a catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism (PMID: 24895169). AMPK has been shown to play a role in inhibiting tumor growth and metastasis (PMID: 24895169) and overexpression of Prkaa1 may promote cell proliferation in gastric cancer cells (PMID: 31558185, PMID: 31841039).


Additional content available in CKB BOOST