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Gene Symbol KDM4D
Synonyms JMJD2D
Gene Description KDM4D, lysine demethylase 4D, is a Jumonji domain histone demethylase and and epigenetic modulator that regulates gene transcription through chromatin remodeling to influence cell growth and differentiation (PMID: 24349617). Kdm4d expression has been linked with resistance to radiotherapy in Hodgkin lymphoma (PMID: 27630312) and nuclear overexpression has been observed in pancreatic cancer (PMID: 29599352).
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