Gene Detail


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Gene Symbol PRKCD
Synonyms ALPS3 | CVID9 | MAY1 | nPKC-delta | PKCD
Gene Description PRKCD, protein kinase C delta, is a serine/threonine-protein kinase that plays a role in both inhibiting and stimulating cell proliferation and apoptosis (PMID: 15054085), and also functions in regulating responses to inflammation (PMID: 29617417). PRKCD signaling has been implicated in tumorigenesis of a variety of human cancers (PMID: 23474764, PMID: 26015399, PMID: 26811494) and a recurrent fusion, LAMTOR1-PRKCD, has been observed in aneurysmal benign fibrous histiocytoma (PMID: 30094855, PMID: 26432191).
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